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The arena was brightly lit all through the test. From the novelty testing, naive animals were placed in the middle with the arena and allowed to discover the chamber for ten min. The habituation screening was performed on the working day following the novelty screening, the place mice had been reintroduced to the arena and allowed to investigate fo

Inhibition of focal adhesion kinase (FAK) rescued SERT function in synapses of KI mice, demonstrating that constitutive Lively FAK signaling downstream of the Pro32Pro33 integrin αvβthree suppresses SERT action. Our reports establish a fancy regulation of 5-HT homeostasis and behaviors by integrin αvβthree, revealing a very important purpose fo